• Immunohistochemistry analysis of UGT2B15 in paraffin-embedded mouse spleen using UGT2B15 Rabbit polyclonal antibody (STJ119076) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of UGT2B15 in paraffin-embedded human oophoroma using UGT2B15 Rabbit polyclonal antibody (STJ119076) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of UGT2B15 in paraffin-embedded rat kidney using UGT2B15 Rabbit polyclonal antibody (STJ119076) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using UGT2B15 Rabbit polyclonal antibody (STJ119076) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-UGT2B15 antibody (60-190) (STJ119076)

SKU:
STJ119076

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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-UGT2B15 (60-190) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UGT2B15
Gene ID: 7366
Uniprot ID: UDB15_HUMAN
Immunogen Region: 60-190
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-190 of human UGT2B15 (NP_001067.2).
Immunogen Sequence: ASTLVNASKSSAIKLEVYPT SLTKNYLEDSLLKILDRWIY GVSKNTFWSYFSQLQELCWE YYDYSNKLCKDAVLNKKLMM KLQESKFDVILADALNPCGE LLAELFNIPFLYSLRFSVGY TFEKNGGGFLF
Tissue Specificity Expressed in many tissues. Present in liver, prostate and testis.
Function UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile. Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds. Catalyzes the glucuronidation of endogenous steroid hormones such as androgens (testosterone, androsterone) and estrogens (estradiol, epiestradiol, estriol, catechol estrogens). Displays glucuronidation activity toward several classes of xenobiotic substrates, including phenolic compounds (eugenol, 4-nitrophenol, 4-hydroxybiphenyl) and phenylpropanoids (naringenin, coumarins). Catalyzes the glucuronidation of monoterpenoid alcohols such as borneol, menthol and isomenthol, a class of natural compounds used in essential oils.
Protein Name Udp-Glucuronosyltransferase 2b15
Udpgt 2b15
Ugt2b15
Hlug4
Udp-Glucuronosyltransferase 2b8
Udpgt 2b8
Udpgth-3
Database Links Reactome: R-HSA-156588
Reactome: R-HSA-9749641
Reactome: R-HSA-9753281
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Udp-Glucuronosyltransferase 2b15 antibody
Anti-Udpgt 2b15 antibody
Anti-Ugt2b15 antibody
Anti-Hlug4 antibody
Anti-Udp-Glucuronosyltransferase 2b8 antibody
Anti-Udpgt 2b8 antibody
Anti-Udpgth-3 antibody
Anti-UGT2B15 antibody
Anti-UGT2B8 antibody

Information sourced from Uniprot.org

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