Western blot analysis of various lysates using UGT1A6 Rabbit polyclonal antibody (STJ11103873) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/ proteins: 25 Mu g per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-UGT1A6 antibody (65-270) (STJ11103873)

SKU:
STJ11103873
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: UGT1A6
Gene ID: 54578
Uniprot ID: UD16_HUMAN
Immunogen Region: 65-270
Specificity: Recombinant Protein corresponding to a sequence within amino acids 65-270 of human UGT1A6 (NP_001063.2).
Immunogen Sequence: LLLKESKYYTRKIYPVPYDQ EELKNRYQSFGNNHFAERSF LTAPQTEYRNNMIVIGLYFI NCQSLLQDRDTLNFFKESKF DALFTDPALPCGVILAEYLG LPSVYLFRGFPCSLEHTFSR SPDPVSYIPRCYTKFSDHMT FSQRVANFLVNLLEPYLFYC LFSKYEELASAVLKRDVDII TLYQKVSVWLLRYDFVLEYP RPVMPN
Tissue Specificity Expressed in skin. Isoforms 1 and 3 are expressed in kidney and liver. Isoform 1 but not isoform 2 is expressed in colon, esophagus and small intestine.
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1.
Protein Name Udp-Glucuronosyltransferase 1-6
Udpgt 1-6
Ugt1*6
Ugt1-06
Ugt1.6
Phenol-Metabolizing Udp-Glucuronosyltransferase
Udp-Glucuronosyltransferase 1-F
Ugt-1f
Ugt1f
Udp-Glucuronosyltransferase 1a6
Database Links Reactome: R-HSA-156588
Reactome: R-HSA-9749641
Reactome: R-HSA-9753281
Cellular Localisation Microsome
Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Udp-Glucuronosyltransferase 1-6 antibody
Anti-Udpgt 1-6 antibody
Anti-Ugt1*6 antibody
Anti-Ugt1-06 antibody
Anti-Ugt1.6 antibody
Anti-Phenol-Metabolizing Udp-Glucuronosyltransferase antibody
Anti-Udp-Glucuronosyltransferase 1-F antibody
Anti-Ugt-1f antibody
Anti-Ugt1f antibody
Anti-Udp-Glucuronosyltransferase 1a6 antibody
Anti-UGT1A6 antibody
Anti-GNT1 antibody
Anti-UGT1 antibody

Information sourced from Uniprot.org

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