| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UBR7 |
| Gene ID: | 55148 |
| Uniprot ID: | UBR7_HUMAN |
| Immunogen Region: | 76-425 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 76-425 of human UBR7 (NP_786924.2). |
| Immunogen Sequence: | LACSYECHGSHKLFELYTKR NFRCDCGNSKFKNLECKLLP DKAKVNSGNKYNDNFFGLYC ICKRPYPDPEDEIPDEMIQC VVCEDWFHGRHLGAIPPESG DFQEMVCQACMKRCSFLWAY AAQLAVTKISTEDDGLVRNI DGIGDQEVIKPENGEHQDST LKEDVPEQGKDDVREVKVEQ NSEPCAGSSSESDLQTVFKN ESLNAESKSGCKLQELKAKQ LIKKDTATYWPLNWRSKLC |
| Tissue Specificity | Expressed in sperm (at protein level). |
| Function | E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. |
| Protein Name | Putative E3 Ubiquitin-Protein Ligase Ubr7 N-Recognin-7 Ring-Type E3 Ubiquitin Transferase Ubr7 |
| Alternative Antibody Names | Anti-Putative E3 Ubiquitin-Protein Ligase Ubr7 antibody Anti-N-Recognin-7 antibody Anti-Ring-Type E3 Ubiquitin Transferase Ubr7 antibody Anti-UBR7 antibody Anti-C14orf130 antibody |
Information sourced from Uniprot.org