| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UBE2J2 |
| Gene ID: | 118424 |
| Uniprot ID: | UB2J2_HUMAN |
| Immunogen Region: | 1-230 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human UBE2J2 (NP_477515.2). |
| Immunogen Sequence: | MSSTSSKRAPTTATQRLKQD YLRIKKDPVPYICAEPLPSN ILEWHYVVRGPEMTPYEGGY YHGKLIFPREFPFKPPSIYM ITPNGRFKCNTRLCLSITDF HPDTWNPAWSVSTILTGLLS FMVEKGPTLGSIETSDFTKR QLAVQSLAFNLKDKVFCELF PEVVEEIKQKQKAQDELSSR PQTLPLPDVVPDGETHLVQN GIQLLNGHAPGAVPNLAGLQ QANRHHGLLG |
| Post Translational Modifications | Auto-ubiquitinated. |
| Function | Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD). In cooperation with the GATOR2 complex, catalyzes 'Lys-6'-linked ubiquitination of NPRL2. |
| Protein Name | Ubiquitin-Conjugating Enzyme E2 J2E2 Ubiquitin-Conjugating Enzyme J2Non-Canonical Ubiquitin-Conjugating Enzyme 2Ncube-2 |
| Database Links | Reactome: R-HSA-8866654 Q8N2K1-1Reactome: R-HSA-9609523 Q8N2K1-1Reactome: R-HSA-983168 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Iv Membrane Protein |
| Alternative Antibody Names | Anti-Ubiquitin-Conjugating Enzyme E2 J2 antibodyAnti-E2 Ubiquitin-Conjugating Enzyme J2 antibodyAnti-Non-Canonical Ubiquitin-Conjugating Enzyme 2 antibodyAnti-Ncube-2 antibodyAnti-UBE2J2 antibodyAnti-NCUBE2 antibody |
Information sourced from Uniprot.org