| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UBE2D2 (1-147) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UBE2D2 |
| Gene ID: |
7322 |
| Uniprot ID: |
UB2D2_HUMAN |
| Immunogen Region: |
1-147 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human UBE2D2 (NP_003330.1). |
| Immunogen Sequence: |
MALKRIHKELNDLARDPPAQ CSAGPVGDDMFHWQATIMGP NDSPYQGGVFFLTIHFPTDY PFKPPKVAFTTRIYHPNINS NGSICLDILRSQWSPALTIS KVLLSICSLLCDPNPDDPLV PEIARIYKTDREKYNRIARE WTQKYAM |
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by RIGI in response to viral infection. Essential for viral activation of IRF3. |
| Protein Name | Ubiquitin-Conjugating Enzyme E2 D2(E3-Independent E2 Ubiquitin-Conjugating Enzyme D2E2 Ubiquitin-Conjugating Enzyme D2Ubiquitin Carrier Protein D2Ubiquitin-Conjugating Enzyme E2(17kb 2Ubiquitin-Conjugating Enzyme E2-17 Kda 2Ubiquitin-Protein Ligase D2P53-Regulated Ubiquitin-Conjugating Enzyme 1 |
| Database Links | Reactome: R-HSA-1234176Reactome: R-HSA-168927Reactome: R-HSA-202424Reactome: R-HSA-2871837Reactome: R-HSA-5357905Reactome: R-HSA-5607764Reactome: R-HSA-8866652Reactome: R-HSA-8866654Reactome: R-HSA-8951664Reactome: R-HSA-9033241Reactome: R-HSA-936440Reactome: R-HSA-937041Reactome: R-HSA-9705462Reactome: R-HSA-983168 |
| Alternative Antibody Names | Anti-Ubiquitin-Conjugating Enzyme E2 D2 antibodyAnti-(E3-Independent E2 Ubiquitin-Conjugating Enzyme D2 antibodyAnti-E2 Ubiquitin-Conjugating Enzyme D2 antibodyAnti-Ubiquitin Carrier Protein D2 antibodyAnti-Ubiquitin-Conjugating Enzyme E2(17kb 2 antibodyAnti-Ubiquitin-Conjugating Enzyme E2-17 Kda 2 antibodyAnti-Ubiquitin-Protein Ligase D2 antibodyAnti-P53-Regulated Ubiquitin-Conjugating Enzyme 1 antibodyAnti-UBE2D2 antibodyAnti-PUBC1 antibodyAnti-UBC4 antibodyAnti-UBC5B antibodyAnti-UBCH4 antibodyAnti-UBCH5B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
