• Immunohistochemical analysis of paraffin-embedded Human Thyroid Tissue using TTR Mouse mAb diluted at 1:200
  • Western blot analysis of Human Serum using TTR Mouse mAb diluted at 1:2000
  • Immunohistochemical analysis of paraffin-embedded Human Liver Carcinoma Tissue using TTR Mouse mAb diluted at 1:200

Anti-TTR antibody (STJ98884)

SKU:
STJ98884

£46.00 - £226.00
Current Stock:
Host: Mouse
Applications: WB/IHC/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Transthyretin is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TTR
Gene ID: 7276
Uniprot ID: TTHY_HUMAN
Specificity: The antibody detects endogenous TTR protein
Immunogen: Recombinant Protein of TTR
Post Translational Modifications Not glycosylated under normal conditions. Following unfolding, caused for example by variant AMYL-TTR 'Gly-38', the cryptic Asn-118 site is exposed and glycosylated by STT3B-containing OST complex, leading to its degradation by the ER-associated degradation (ERAD) pathway. Sulfonation of the reactive cysteine Cys-30 enhances the stability of the native conformation of TTR, avoiding misassembly of the protein leading to amyloid formation.
Function Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Protein Name Transthyretin
Attr
Prealbumin
Tbpa
Database Links Reactome: R-HSA-2453864
Reactome: R-HSA-2453902
Reactome: R-HSA-3000171
Reactome: R-HSA-6798695
Reactome: R-HSA-975634
Reactome: R-HSA-977225
Cellular Localisation Secreted
Cytoplasm
Alternative Antibody Names Anti-Transthyretin antibody
Anti-Attr antibody
Anti-Prealbumin antibody
Anti-Tbpa antibody
Anti-TTR antibody
Anti-PALB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance