| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TSPYL5 |
| Gene ID: | 85453 |
| Uniprot ID: | TSYL5_HUMAN |
| Immunogen Region: | 201-383 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 201-383 of human TSPYL5 (NP_277047.2). |
| Immunogen Sequence: | SMDTLENVQLKLENMNAQAD RAYLRLSRKFGQLRLQHLER RNHLIQNIPGFWGQAFQNHP QLASFLNSQEKEVLSYLNSL EVEELGLARLGYKIKFYFDR NPYFQNKVLIKEYGCGPSGQ VVSRSTPIQWLPGHDLQSLS QGNPENNRSFFGWFSNHSSI ESDKIVEIINEELWPNPLQF YLL |
| Function | Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination.the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7. |
| Protein Name | Testis-Specific Y-Encoded-Like Protein 5Tspy-Like Protein 5 |
| Alternative Antibody Names | Anti-Testis-Specific Y-Encoded-Like Protein 5 antibodyAnti-Tspy-Like Protein 5 antibodyAnti-TSPYL5 antibodyAnti-KIAA1750 antibody |
Information sourced from Uniprot.org