| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TRIT1 (48-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TRIT1 |
| Gene ID: |
54802 |
| Uniprot ID: |
MOD5_HUMAN |
| Immunogen Region: |
48-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 48-300 of human TRIT1 (NP_060116.2). |
| Immunogen Sequence: |
GGEIVSADSMQVYEGLDIIT NKVSAQEQRICRHHMISFVD PLVTNYTVVDFRNRATALIE DIFARDKIPIVVGGTNYYIE SLLWKVLVNTKPQEMGTEKV IDRKVELEKEDGLVLHKRLS QVDPEMAAKLHPHDKRKVAR SLQVFEETGISHSEFLHRQH TEEGGGPLGGPLKFSNPCIL WLHADQAVLDERLDKRVDDM LAAGLLEELRDFHRRYNQKN VSENSQDYQHGIFQSIGFK |
| Function | Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i6A37). Mediates modification of a limited subset of tRNAs: tRNA(Ser)(AGA), tRNA(Ser)(CGA), tRNA(Ser)(UGA), as well as partial modification of the selenocysteine tRNA(Ser)(UCA). TRIT1 is therefore required for selenoprotein expression. |
| Protein Name | Trna DimethylallyltransferaseIsopentenyl-Diphosphate -Trna IsopentenyltransferaseIpp TransferaseIpptHgro1Trna Isopentenyltransferase 1Iptase |
| Database Links | Reactome: R-HSA-6782315Reactome: R-HSA-6787450 |
| Cellular Localisation | Isoform 1: MitochondrionIsoform 4: MitochondrionIsoform 2: CytoplasmIsoform 3: CytoplasmIsoform 5: Cytoplasm |
| Alternative Antibody Names | Anti-Trna Dimethylallyltransferase antibodyAnti-Isopentenyl-Diphosphate -Trna Isopentenyltransferase antibodyAnti-Ipp Transferase antibodyAnti-Ippt antibodyAnti-Hgro1 antibodyAnti-Trna Isopentenyltransferase 1 antibodyAnti-Iptase antibodyAnti-TRIT1 antibodyAnti-IPT antibodyAnti-MOD5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
