| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TPSB2 |
| Gene ID: | 64499 |
| Uniprot ID: | TRYB2_HUMAN |
| Immunogen Region: | 1-275 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human Mast Cell Tryptase (Mast Cell Tryptase (TPSB2) ) (NP_077078.5). |
| Immunogen Sequence: | MLNLLLLALPVLASRAYAAP APGQALQRVGIVGGQEAPRS KWPWQVSLRVRDRYWMHFCG GSLIHPQWVLTAAHCVGPDV KDLAALRVQLREQHLYYQDQ LLPVSRIIVHPQFYTAQIGA DIALLELEEPVNVSSHVHTV TLPPASETFPPGMPCWVTGW GDVDNDERLPPPFPLKQVKV PIMENHICDAKYHLGAYTGD DVRIVRDDMLCAGNTRRDSC QGDSGGPLVCKVNGTWLQA |
| Function | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. |
| Protein Name | Tryptase Beta-2Tryptase-2Tryptase Ii |
| Cellular Localisation | SecretedReleased From The Secretory Granules Upon Mast Cell Activation |
| Alternative Antibody Names | Anti-Tryptase Beta-2 antibodyAnti-Tryptase-2 antibodyAnti-Tryptase Ii antibodyAnti-TPSB2 antibodyAnti-TPS2 antibody |
Information sourced from Uniprot.org