| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:100-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMOD3 |
| Gene ID: | 29766 |
| Uniprot ID: | TMOD3_HUMAN |
| Immunogen Region: | 1-352 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-352 of human TMOD3 (NP_055362.1). |
| Immunogen Sequence: | MALPFRKDLEKYKDLDEDEL LGNLSETELKQLETVLDDLD PENALLPAGFRQKNQTSKST TGPFDREHLLSYLEKEALEH KDREDYVPYTGEKKGKIFIP KQKPVQTFTEEKVSLDPELE EALTSASDTELCDLAAILGM HNLITNTKFCNIMGSSNGVD QEHFSNVVKGEKILPVFDEP PNPTNVEESLKRTKENDAHL VEVNLNNIKNIPIPTLKDFA KALETNTHVKCFSLAATRS |
| Tissue Specificity | Ubiquitous. |
| Function | Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. |
| Protein Name | Tropomodulin-3Ubiquitous TropomodulinU-Tmod |
| Database Links | Reactome: R-HSA-390522Reactome: R-HSA-9013418Reactome: R-HSA-9696264 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Tropomodulin-3 antibodyAnti-Ubiquitous Tropomodulin antibodyAnti-U-Tmod antibodyAnti-TMOD3 antibody |
Information sourced from Uniprot.org