| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TMEM74 (1-180) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TMEM74 |
| Gene ID: |
157753 |
| Uniprot ID: |
TMM74_HUMAN |
| Immunogen Region: |
1-180 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human TMEM74 (NP_694560.1). |
| Immunogen Sequence: |
MELHYLAKKSNQADLCDARD WSSRGLPGDQADTAATRAAL CCQKQCASTPRATEMEGSKL SSSPASPSSSLQNSTLQPDA FPPGLLHSGNNQITAERKVC NCCSQELETSFTYVDKNINL EQRNRSSPSAKGHNHPGELG WENPNEWSQEAAISLISEEE DDTSSEATSSGKSIDYGFIS |
| Tissue Specificity | Expressed in heart, lung, and placenta. |
| Function | Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction. |
| Protein Name | Transmembrane Protein 74 |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane ProteinCytoplasmic VesicleAutophagosome Membrane |
| Alternative Antibody Names | Anti-Transmembrane Protein 74 antibodyAnti-TMEM74 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
