• Western blot analysis of extracts of various cell lines, using TM6SF2 antibody (STJ11100579) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-TM6SF2 antibody (290-377) (STJ11100579)

SKU:
STJ11100579

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TM6SF2 (290-377) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TM6SF2
Gene ID: 53345
Uniprot ID: TM6S2_HUMAN
Immunogen Region: 290-377
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 290-377 of human TM6SF2 (NP_001001524.2).
Immunogen Sequence: PGCSWLPDWALVFAGGIGQA QFSHMGASMHLRTPFTYRVP EDTWGCFFVCNLLYALGPHL LAYRCLQWPAFFHQPPPSDP LALHKKQH
Tissue Specificity Substantial expression in liver and intestine, whereas all other tissues analyzed show low levels.
Function Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content. May function as sterol isomerase.
Protein Name Transmembrane 6 Superfamily Member 2
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Alternative Antibody Names Anti-Transmembrane 6 Superfamily Member 2 antibody
Anti-TM6SF2 antibody

Information sourced from Uniprot.org

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