| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TM6SF2 |
| Gene ID: | 53345 |
| Uniprot ID: | TM6S2_HUMAN |
| Immunogen Region: | 290-377 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-377 of human TM6SF2 (NP_001001524.2). |
| Immunogen Sequence: | PGCSWLPDWALVFAGGIGQA QFSHMGASMHLRTPFTYRVP EDTWGCFFVCNLLYALGPHL LAYRCLQWPAFFHQPPPSDP LALHKKQH |
| Tissue Specificity | Substantial expression in liver and intestine, whereas all other tissues analyzed show low levels. |
| Function | Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content. May function as sterol isomerase. |
| Protein Name | Transmembrane 6 Superfamily Member 2 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum-Golgi Intermediate Compartment Membrane |
| Alternative Antibody Names | Anti-Transmembrane 6 Superfamily Member 2 antibodyAnti-TM6SF2 antibody |
Information sourced from Uniprot.org