| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TIE1 (350-600) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TIE1 |
| Gene ID: |
7075 |
| Uniprot ID: |
TIE1_HUMAN |
| Immunogen Region: |
350-600 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 350-600 of human TIE1 (NP_005415.1). |
| Immunogen Sequence: |
IPQILNMASELEFNLETMPR INCAAAGNPFPVRGSIELRK PDGTVLLSTKAIVEPEKTTA EFEVPRLVLADSGFWECRVS TSGGQDSRRFKVNVKVPPVP LAAPRLLTKQSRQLVVSPLV SFSGDGPISTVRLHYRPQDS TMDWSTIVVDPSENVTLMNL RPKTGYSVRVQLSRPGEGGE GAWGPPTLMTTDCPEPLLQP WLEGWHVEGTDRLRVSWSLP LVPGPLVGDGFLLRLWDGT |
| Tissue Specificity | Specifically expressed in developing vascular endothelial cells. |
| Post Translational Modifications | Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2. |
| Function | Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. |
| Protein Name | Tyrosine-Protein Kinase Receptor Tie-1 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tyrosine-Protein Kinase Receptor Tie-1 antibodyAnti-TIE1 antibodyAnti-TIE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
