Host: | Goat |
Applications: | Pep-ELISA/WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-TFEC (N-Term) is suitable for use in ELISA and Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 40-45kDa band seen in Human Testis lysate. Recommended for use at 0.5-2µg/ml. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | TFEC |
Gene ID: | 22797 |
Uniprot ID: | TFEC_HUMAN |
Immunogen Region: | N-Term |
Accession Number: | NP_036384.1; NP_001018068.1 |
Specificity: | This antibody is expected to recognise both reported Human isoforms according to NP_036384.1 and NP_001018068.1. |
Immunogen Sequence: | TLDHQIINPTLK |
Function | Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form. |
Protein Name | Transcription Factor EcTfe-CClass E Basic Helix-Loop-Helix Protein 34Bhlhe34Transcription Factor Ec-LikeHtfec-L |
Database Links | Reactome: R-HSA-9856649 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Transcription Factor Ec antibodyAnti-Tfe-C antibodyAnti-Class E Basic Helix-Loop-Helix Protein 34 antibodyAnti-Bhlhe34 antibodyAnti-Transcription Factor Ec-Like antibodyAnti-Htfec-L antibodyAnti-TFEC antibodyAnti-BHLHE34 antibodyAnti-TCFEC antibodyAnti-TFECL antibody |
Information sourced from Uniprot.org