• Western blot analysis of various lysates using TEX2 Rabbit polyclonal antibody (STJ116888) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-TEX2 antibody (915-1134) (STJ116888)

SKU:
STJ116888

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TEX2 (915-1134) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TEX2
Gene ID: 55852
Uniprot ID: TEX2_HUMAN
Immunogen Region: 915-1134
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 915-1134 of human TEX2 (NP_060939.3).
Immunogen Sequence: LETKMNLTKLGKEPLVEALK VGEIGKEGCRPRAFCLADSD EESSSAGSSEEDDAPEPSGG DKQLLPGAEGYVGGHRTSKI MRFVDKITKSKYFQKATETE FIKKKIEEVSNTPLLLTVEV QECRGTLAVNIPPPPTDRVW YGFRKPPHVELKARPKLGER EVTLVHVTDWIEKKLEQEFQ KVFVMPNMDDVYITIMHSAM DPRSTSCLLKDPPVEAADQP
Function During endoplasmic reticulum (ER) stress or when cellular ceramide levels increase, may induce contacts between the ER and medial-Golgi complex to facilitate non-vesicular transport of ceramides from the ER to the Golgi complex where they are converted to complex sphingolipids, preventing toxic ceramide accumulation.
Protein Name Testis-Expressed Protein 2
Transmembrane Protein 96
Database Links Reactome: R-HSA-8980692
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Nucleus Membrane
Enriched At The Nucleus-Vacuole Junction
During Endoplasmic Reticulum (Er) Stress
Localizes To Er-Golgi Contacts
Alternative Antibody Names Anti-Testis-Expressed Protein 2 antibody
Anti-Transmembrane Protein 96 antibody
Anti-TEX2 antibody
Anti-KIAA1738 antibody
Anti-TMEM96 antibody

Information sourced from Uniprot.org

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