Anti-TCR Gamma/Delta antibody [B1] {FITC} (STJA0000908)

SKU:
STJA0000908
$173.48 - $362.48
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Host: Mouse
Applications: FC
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-TCR Gamma/Delta is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : B1
Conjugation: FITC
Isotype: IgG1k
Formulation: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration: 5 Mu L/Test
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Background CD49d is a 150 kD Alpha integrin chain known as Alpha 4 integrin or VLA-4 Alpha chain. It forms a heterodimer with either integrin Beta 1 ( Alpha 4 Beta 1, VLA-4) or Beta 7 ( Alpha 4 Beta 7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. Alpha 4 Beta 7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

Information sourced from Uniprot.org