| Host: | Mouse |
| Applications: | IF/IP/IHC-P/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-TALIN-1 is suitable for use in Immunofluorescence, Immunoprecipitation, Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 97H6 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | PBS with <0.1% sodium azide |
| Purification: | Purified |
| Concentration: | 1 mg/mL |
| Storage Instruction: | Store aliquots at-20°C, and thawed aliquots at 2-8°C. |
| Immunogen: | his-tagged polypeptide containing residues 489–911 of mouse talin1 |
| Background | Mouse anti Human Talin-1 antibody, clone 97H6 recognizes an epitope within the region of amino acids 482-655 of humanTalin-1, a high molecular weight cytoskeletal protein, linking vinculin to the integrins, thereby linking the cytoskeleton to the extracellular matrix. It is specifically found in regions of cell-substratum contact and in lymphocytes at cell-cell contact points. Talin-1 plays a role in the assembly of actin filaments and in the migration of cells such as osteoclasts and fibroblasts |
Information sourced from Uniprot.org