| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SUN5 (125-270) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SUN5 |
| Gene ID: |
140732 |
| Uniprot ID: |
SUN5_HUMAN |
| Immunogen Region: |
125-270 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 125-270 of human SUN5 (NP_542406.2). |
| Immunogen Sequence: |
KMKVWQDDSINGPLQSLRLY QEKVRHHSGEIQDLRGSMNQ LIAKLQEMEAMSDEQKMAQK IMKMIHGDYIEKPDFALKSI GASIDFEHTSVTYNHEKAHS YWNWIQLWNYAQPPDVILEP NVTPGNCWAFEGDRGQVTIQ LAQKVY |
| Tissue Specificity | Sperm (at protein level). Widely expressed. Conflictingly shown to be specifically expressed in testis. |
| Post Translational Modifications | Highly glycosylated in the Golgi apparatus during spermiogenesis. |
| Function | Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope. |
| Protein Name | Sun Domain-Containing Protein 5Sad1 And Unc84 Domain-Containing Protein 5Sperm-Associated Antigen 4-Like ProteinTestis And Spermatogenesis-Related Gene 4 Protein |
| Cellular Localisation | Nucleus Inner MembraneSingle-Pass Membrane ProteinGolgi ApparatusDuring SpermiogenesisTraffics Through The Golgi Apparatus Before Reaching The Round Spermatid Inner Membrane Of The Nuclear Envelope And Later Migrates To The Coupling Apparatus Of The Sperm During Sperm Head Elongation And DifferentiationIn Mature SpermatozoaIs Localized To The Coupling Apparatus Of The Sperm Head And Tail In The Implementation Fossa |
| Alternative Antibody Names | Anti-Sun Domain-Containing Protein 5 antibodyAnti-Sad1 And Unc84 Domain-Containing Protein 5 antibodyAnti-Sperm-Associated Antigen 4-Like Protein antibodyAnti-Testis And Spermatogenesis-Related Gene 4 Protein antibodyAnti-SUN5 antibodyAnti-SPAG4L antibodyAnti-TSARG4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
