Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SULT1C2 |
Gene ID: | 6819 |
Uniprot ID: | ST1C2_HUMAN |
Immunogen Region: | 1-120 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SULT1C2 (NP_001047.1). |
Immunogen Sequence: | MALTSDLGKQIKLKEVEGTL LQPATVDNWSQIQSFEAKPD DLLICTYPKAGTTWIQEIVD MIEQNGDVEKCQRAIIQHRH PFIEWARPPQPSGVEKAKAM PSPRILKTHLSTQLLPPSFW |
Tissue Specificity | Found in adult stomach, kidney and thyroid gland, and in fetal kidney and liver. |
Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic compounds. Does not sulfonate steroids, dopamine, acetaminophen, or alpha-naphthol. Catalyzes the sulfonation of the carcinogenic N-Hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis. |
Protein Name | Sulfotransferase 1c2St1c2Sulfotransferase 1c1Sult1c#1Humsultc2 |
Database Links | Reactome: R-HSA-156584 |
Cellular Localisation | CytoplasmLysosome |
Alternative Antibody Names | Anti-Sulfotransferase 1c2 antibodyAnti-St1c2 antibodyAnti-Sulfotransferase 1c1 antibodyAnti-Sult1c#1 antibodyAnti-Humsultc2 antibodyAnti-SULT1C2 antibodyAnti-SULT1C1 antibody |
Information sourced from Uniprot.org