| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Syntaxin-binding protein 4 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STXBP4 |
| Gene ID: | 252983 |
| Uniprot ID: | STXB4_HUMAN |
| Specificity: | This antibody detects endogenous levels of STXBP4 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human STXBP4 |
| Function | Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose. |
| Protein Name | Syntaxin-Binding Protein 4Syntaxin 4-Interacting ProteinStx4-Interacting ProteinSynip |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Syntaxin-Binding Protein 4 antibodyAnti-Syntaxin 4-Interacting Protein antibodyAnti-Stx4-Interacting Protein antibodyAnti-Synip antibodyAnti-STXBP4 antibody |
Information sourced from Uniprot.org