| Function | RNA-binding protein required for the microtubule-dependent transport of neuronal RNA from the cell body to the dendrite. As protein synthesis occurs within the dendrite, the localization of specific mRNAs to dendrites may be a prerequisite for neurite outgrowth and plasticity at sites distant from the cell body. |
| Protein Name | Double-Stranded Rna-Binding Protein Staufen Homolog 2 |
| Cellular Localisation | CytoplasmNucleusNucleolusEndoplasmic ReticulumShuttles Between The NucleolusNucleus And The CytoplasmNuclear Export Of Isoform 1 Is Independent Of Xpo1/Crm1 And Requires The Exportin Xpo5Nuclear Export Of Isoform 2 And Isoform 3 Can Occur By Both Xpo1/Crm1-Dependent And Xpo1/Crm1-Independent PathwaysFound In Large Cytoplasmic Ribonucleoprotein (Rnp) Granules Which Are Present In The Actin Rich Regions Of Myelinating Processes And Associated With MicrotubulesPolysomes And The Endoplasmic ReticulumAlso Recruited To Stress Granules (Sgs) Upon Inhibition Of Translation Or Oxidative StressThese Structures Are Thought To Harbor Housekeeping Mrnas When Translation Is Aborted |
| Alternative Antibody Names | Anti-Double-Stranded Rna-Binding Protein Staufen Homolog 2 antibodyAnti-STAU2 antibody |
Information sourced from Uniprot.org
