• Immunofluorescence analysis of U2OS cells using STAU2 antibody (STJ116052) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using STAU2 antibody (STJ116052) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-STAU2 antibody (300-400) (STJ116052)

SKU:
STJ116052

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-STAU2 (300-400) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STAU2
Gene ID: 27067
Uniprot ID: STAU2_HUMAN
Immunogen Region: 300-400
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human STAU2 (NP_001157852.1).
Immunogen Sequence: PEYGQGMNPISRLAQIQQAK KEKEPDYVLLSERGMPRRRE FVMQVKVGNEVATGTGPNKK IAKKNAAEAMLLQLGYKAST NLQDQLEKTGENKGWSGPKP G
Function RNA-binding protein required for the microtubule-dependent transport of neuronal RNA from the cell body to the dendrite. As protein synthesis occurs within the dendrite, the localization of specific mRNAs to dendrites may be a prerequisite for neurite outgrowth and plasticity at sites distant from the cell body.
Protein Name Double-Stranded Rna-Binding Protein Staufen Homolog 2
Cellular Localisation Cytoplasm
Nucleus
Nucleolus
Endoplasmic Reticulum
Shuttles Between The Nucleolus
Nucleus And The Cytoplasm
Nuclear Export Of Isoform 1 Is Independent Of Xpo1/Crm1 And Requires The Exportin Xpo5
Nuclear Export Of Isoform 2 And Isoform 3 Can Occur By Both Xpo1/Crm1-Dependent And Xpo1/Crm1-Independent Pathways
Found In Large Cytoplasmic Ribonucleoprotein (Rnp) Granules Which Are Present In The Actin Rich Regions Of Myelinating Processes And Associated With Microtubules
Polysomes And The Endoplasmic Reticulum
Also Recruited To Stress Granules (Sgs) Upon Inhibition Of Translation Or Oxidative Stress
These Structures Are Thought To Harbor Housekeeping Mrnas When Translation Is Aborted
Alternative Antibody Names Anti-Double-Stranded Rna-Binding Protein Staufen Homolog 2 antibody
Anti-STAU2 antibody

Information sourced from Uniprot.org

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