| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-STAP2 (130-220) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
STAP2 |
| Gene ID: |
55620 |
| Uniprot ID: |
STAP2_HUMAN |
| Immunogen Region: |
130-220 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 130-220 of human STAP2 (NP_001013863). |
| Immunogen Sequence: |
GHLYMMSEVLAKEEARRALE TPSCFLKVSRLEAQLLLERY PECGNLLLRPSGDGADGVSV TTRQMHNGTHVVRHYKVKRE GPKYVIDVEQP |
| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | Phosphorylated on tyrosine. Tyr-250 may be important for interaction with kinases. Phosphorylated by PTK6 at Tyr-250 modulates PTK6-mediated STAT3 activation. Tyr-22 and Tyr-322 appears to be phosphorylated by SRC. |
| Function | Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity. |
| Protein Name | Signal-Transducing Adaptor Protein 2Stap-2Breast Tumor Kinase SubstrateBrk Substrate |
| Database Links | Reactome: R-HSA-8849474Reactome: R-HSA-9707564 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Signal-Transducing Adaptor Protein 2 antibodyAnti-Stap-2 antibodyAnti-Breast Tumor Kinase Substrate antibodyAnti-Brk Substrate antibodyAnti-STAP2 antibodyAnti-BKS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
