| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STAC |
| Gene ID: | 6769 |
| Uniprot ID: | STAC_HUMAN |
| Immunogen Region: | 153-402 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 153-402 of human STAC (NP_003140.1). |
| Immunogen Sequence: | GLAPQRCMGKLPKGFRRYYS SPLLIHEQFGCIKEVMPIAC GNKVDPVYETLRFGTSLAQR TKKGSSGSGSDSPHRTSTSD LVEVPEEANGPGGGYDLRKR SNSVFTYPENGTDDFRDPAK NINHQGSLSKDPLQMNTYVA LYKFVPQENEDLEMRPGDII TLLEDSNEDWWKGKIQDRIG FFPANFVQRLQQNEKIFRCV RTFIGCKEQGQITLKENQIC VSSEEEQDGFIRVLSGKKK |
| Function | Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity. Plays a minor and redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C. |
| Protein Name | Sh3 And Cysteine-Rich Domain-Containing ProteinSrc Homology 3 And Cysteine-Rich Domain-Containing Protein |
| Cellular Localisation | CytoplasmCytosolCell MembranePeripheral Membrane ProteinCytoplasmic SideSarcolemma |
| Alternative Antibody Names | Anti-Sh3 And Cysteine-Rich Domain-Containing Protein antibodyAnti-Src Homology 3 And Cysteine-Rich Domain-Containing Protein antibodyAnti-STAC antibodyAnti-STAC1 antibody |
Information sourced from Uniprot.org