| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SRP19 |
| Gene ID: | 6728 |
| Uniprot ID: | SRP19_HUMAN |
| Immunogen Region: | 1-144 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human SRP19 (NP_003126.1). |
| Immunogen Sequence: | MACAAARSPADQDRFICIYP AYLNNKKTIAEGRRIPISKA VENPTATEIQDVCSAVGLNV FLEKNKMYSREWNRDVQYRG RVRVQLKQEDGSLCLVQFPS RKSVMLYAAEMIPKLKTRTQ KTGGADQSLQQGEGSKKGKG KKKK |
| Function | Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds directly to 7SL RNA. Mediates binding of SRP54 to the SRP complex. |
| Protein Name | Signal Recognition Particle 19 Kda ProteinSrp19 |
| Database Links | Reactome: R-HSA-1799339 |
| Cellular Localisation | CytoplasmNucleusNucleolusNucleoplasmAlthough The Signal Recognition Particle Complex Acts In The CytoplasmIt Assembles At Least In Part In The Nucleus And/Or The NucleolusSrp19 Nuclear Import May Be Mediated By Ipo8/Imp8 And Tpno1/Trn |
| Alternative Antibody Names | Anti-Signal Recognition Particle 19 Kda Protein antibodyAnti-Srp19 antibodyAnti-SRP19 antibody |
Information sourced from Uniprot.org