Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SNX4 (1-250) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:200-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SNX4 |
Gene ID: |
8723 |
Uniprot ID: |
SNX4_HUMAN |
Immunogen Region: |
1-250 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human SNX4 (NP_003785.1). |
Immunogen Sequence: |
MEQAPPDPERQLQPAPLEPL GSPDAGLGAAVGKEAEGAGE ESSGVDTMTHNNFWLKKIEI SVSEAEKRTGRNAMNMQETY TAYLIETRSVEHTDGQSVLT DSLWRRYSEFELLRSYLLVY YPHIVVPPLPEKRAEFVWHK LSADNMDPDFVERRRIGLEN FLLRIASHPILCRDKIFYLF LTQEGNWKETVNETGFQLKA DSRLKALNATFRVKNPDKRF TDLKHYSDELQSVISHLLR |
Function | Involved in the regulation of endocytosis and in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation. Involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A. |
Protein Name | Sorting Nexin-4 |
Cellular Localisation | Early Endosome MembranePeripheral Membrane ProteinCytoplasmic SideAlso Detected On A Juxtanuclear Endocytic Recycling Compartment (Erc) |
Alternative Antibody Names | Anti-Sorting Nexin-4 antibodyAnti-SNX4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance