| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SNX4 |
| Gene ID: | 8723 |
| Uniprot ID: | SNX4_HUMAN |
| Immunogen Region: | 1-250 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human SNX4 (NP_003785.1). |
| Immunogen Sequence: | MEQAPPDPERQLQPAPLEPL GSPDAGLGAAVGKEAEGAGE ESSGVDTMTHNNFWLKKIEI SVSEAEKRTGRNAMNMQETY TAYLIETRSVEHTDGQSVLT DSLWRRYSEFELLRSYLLVY YPHIVVPPLPEKRAEFVWHK LSADNMDPDFVERRRIGLEN FLLRIASHPILCRDKIFYLF LTQEGNWKETVNETGFQLKA DSRLKALNATFRVKNPDKRF TDLKHYSDELQSVISHLLR |
| Function | Involved in the regulation of endocytosis and in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation. Involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A. |
| Protein Name | Sorting Nexin-4 |
| Cellular Localisation | Early Endosome MembranePeripheral Membrane ProteinCytoplasmic SideAlso Detected On A Juxtanuclear Endocytic Recycling Compartment (Erc) |
| Alternative Antibody Names | Anti-Sorting Nexin-4 antibodyAnti-SNX4 antibody |
Information sourced from Uniprot.org