Anti-SLPI antibody [31] {Biotin} (STJ16100139)

SKU:
STJ16100139-05

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Host: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-SLPI is suitable for use in research applications.
Clonality: Monoclonal
Clone ID: 31
Conjugation: Biotin
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Storage Instruction: Store at 2-8°C upon receipt.
Gene Symbol: SLPI
Gene ID: 6590
Uniprot ID: SLPI_HUMAN
Function Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses. Has antimicrobial activity against mycobacteria, but not against salmonella. Contributes to normal resistance against infection by M.tuberculosis. Required for normal resistance to infection by L.major. Required for normal wound healing, probably by preventing tissue damage by limiting protease activity. Together with ELANE, required for normal differentiation and proliferation of bone marrow myeloid cells.
Protein Name Antileukoproteinase
Alp
Blpi
Husi-1
Mucus Proteinase Inhibitor
Mpi
Protease Inhibitor Wap4
Secretory Leukocyte Protease Inhibitor
Seminal Proteinase Inhibitor
Wap Four-Disulfide Core Domain Protein 4
Database Links Reactome: R-HSA-6798695
Cellular Localisation Secreted
Alternative Antibody Names Anti-Antileukoproteinase antibody
Anti-Alp antibody
Anti-Blpi antibody
Anti-Husi-1 antibody
Anti-Mucus Proteinase Inhibitor antibody
Anti-Mpi antibody
Anti-Protease Inhibitor Wap4 antibody
Anti-Secretory Leukocyte Protease Inhibitor antibody
Anti-Seminal Proteinase Inhibitor antibody
Anti-Wap Four-Disulfide Core Domain Protein 4 antibody
Anti-SLPI antibody
Anti-WAP4 antibody
Anti-WFDC4 antibody

Information sourced from Uniprot.org

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