Western blot analysis of extracts of various cell lines, using SLMAP antibody (STJ116579) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-SLMAP antibody (540-790) (STJ116579)

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STJ116579
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLMAP
Gene ID: 7871
Uniprot ID: SLMAP_HUMAN
Immunogen Region: 540-790
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 540-790 of human SLMAP (NP_009090.2).
Immunogen Sequence: IDTENLREEKDSEITSTRDE LLSARDEILLLHQAAAKVAS ERDTDIASLQEELKKVRAEL ERWRKAASEYEKEITSLQNS FQLRCQQCEDQQREEATRLQ GELEKLRKEWNALETECHSL KRENVLLSSELQRQEKELHN SQKQSLELTSDLSILQMSRK ELENQVGSLKEQHLRDSADL KTLLSKAENQAKDVQKEYEK TQTVLSELKLKFEMTEQEKQ SITDELKQCKNNLKLLREK
Function Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth. May play a role during myoblast fusion.
Protein Name Sarcolemmal Membrane-Associated Protein
Sarcolemmal-Associated Protein
Cellular Localisation Cell Membrane
Sarcolemma
Single-Pass Type Iv Membrane Protein
Cytoplasm
Myofibril
Sarcomere
M Line
Z Line
Cytoskeleton
Microtubule Organizing Center
Centrosome
Membrane-Associated
Distributed In The Transverse Tubules And Near The Junctional Sarcoplasmic Reticulum
Detected Along The Z- And M-Lines In Cardiomyocytes
Isoform 1: Endoplasmic Reticulum Membrane
Mitochondrion Membrane
Isoform 2: Endoplasmic Reticulum Membrane
Isoform 3: Endoplasmic Reticulum Membrane
Isoform 4: Endoplasmic Reticulum Membrane
Isoform 5: Endoplasmic Reticulum Membrane
Do Not Localize At The Mitochondrial Membrane
Alternative Antibody Names Anti-Sarcolemmal Membrane-Associated Protein antibody
Anti-Sarcolemmal-Associated Protein antibody
Anti-SLMAP antibody
Anti-KIAA1601 antibody
Anti-SLAP antibody
Anti-UNQ1847 antibody
Anti-PRO3577 antibody

Information sourced from Uniprot.org

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