| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human/Mouse/Rat/Dog/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SLITRK1 (C-Term) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary experiments in human brain lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedback from people in the |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SLITRK1 |
| Gene ID: | 114798 |
| Uniprot ID: | SLIK1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_443142.1 |
| Immunogen Sequence: | NADGAHRVYDCGSHS |
| Post Translational Modifications | Undergoes proteolytic cleavage that results in shedding of the ectodomain and cleavage of the C-terminal cytoplasmic tail. Glycosylated. Phosphorylation at Ser-695 is necessary for proper function in promoting neurite outgrowth. |
| Function | It is involved in synaptogenesis and promotes excitatory synapse differentiation. Enhances neuronal dendrite outgrowth. |
| Protein Name | Slit And Ntrk-Like Protein 1Leucine-Rich Repeat-Containing Protein 12 |
| Database Links | Reactome: R-HSA-388844 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecretedSynapse |
| Alternative Antibody Names | Anti-Slit And Ntrk-Like Protein 1 antibodyAnti-Leucine-Rich Repeat-Containing Protein 12 antibodyAnti-SLITRK1 antibodyAnti-KIAA1910 antibodyAnti-LRRC12 antibodyAnti-UNQ233 antibodyAnti-PRO266 antibody |
Information sourced from Uniprot.org