| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC44A4 (65-215) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC44A4 |
| Gene ID: |
80736 |
| Uniprot ID: |
CTL4_HUMAN |
| Immunogen Region: |
65-215 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 65-215 of human SLC44A4 (NP_079533.2). |
| Immunogen Sequence: |
LYPRNSTGAYCGMGENKDKP YLLYFNIFSCILSSNIISVA ENGLQCPTPQVCVSSCPEDP WTVGKNEFSQTVGEVFYTKN RNFCLPGVPWNMTVITSLQQ ELCPSFLLPSAPALGRCFPW TNVTPPALPGITNDTTIQQG ISGLIDSLNAR |
| Tissue Specificity | Highly expressed in colon, also detected in prostate, trachea and lung. Isoform 3 is also expressed in colon but a lower levels. Isoform 3: Expressed in colon at low levels. |
| Post Translational Modifications | N-glycosylated.N-glycosylation of Asn-69, Asn-155 and Asn-393 is required for a proper thiamine pyrophosphate uptake. |
| Function | Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury. Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis. Isoform 3: Has also thiamine pyrophosphate transporter activity. |
| Protein Name | Choline Transporter-Like Protein 4Solute Carrier Family 44 Member 4Thiamine Pyrophosphate Transporter 1Htppt1 |
| Database Links | Reactome: R-HSA-1483191Reactome: R-HSA-425366 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Choline Transporter-Like Protein 4 antibodyAnti-Solute Carrier Family 44 Member 4 antibodyAnti-Thiamine Pyrophosphate Transporter 1 antibodyAnti-Htppt1 antibodyAnti-SLC44A4 antibodyAnti-C6orf29 antibodyAnti-CTL4 antibodyAnti-NG22 antibodyAnti-TPPT1 antibodyAnti-UNQ441 antibodyAnti-PRO874 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
