Anti-SLC29A1/hENT1 antibody [SAA1893] (STJA0020321)

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STJA0020321
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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Equilibrative Nucleoside Transporter 1 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1893
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: SLC29A1
Gene ID: 2030
Uniprot ID: S29A1_HUMAN
Post Translational Modifications Glycosylated.
Function Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier. Regulates inosine levels in brown adipocytes tissues (BAT) and extracellular inosine levels, which controls BAT-dependent energy expenditure.
Protein Name Equilibrative Nucleoside Transporter 1
Hent1
Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter
Equilibrative Nbmpr-Sensitive Nucleoside Transporter
Es Nucleoside Transporter
Nucleoside Transporter - Es-Type
Solute Carrier Family 29 Member 1
Database Links Reactome: R-HSA-83936
Reactome: R-HSA-9748787
Reactome: R-HSA-9755088
Cellular Localisation Basolateral Cell Membrane
Multi-Pass Membrane Protein
Apical Cell Membrane
Cell Membrane
Localized To The Basolateral Membrane Of Sertoli Cells
Localized To The Cell Membrane Of Erythrocytes
Alternative Antibody Names Anti-Equilibrative Nucleoside Transporter 1 antibody
Anti-Hent1 antibody
Anti-Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter antibody
Anti-Equilibrative Nbmpr-Sensitive Nucleoside Transporter antibody
Anti-Es Nucleoside Transporter antibody
Anti-Nucleoside Transporter - Es-Type antibody
Anti-Solute Carrier Family 29 Member 1 antibody
Anti-SLC29A1 antibody
Anti-ENT1 antibody

Information sourced from Uniprot.org