Tissue Specificity | Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus. |
Post Translational Modifications | Phosphorylated. |
Function | Sodium:ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate. Has retained some ancestral activity toward nucleobases such as urate, an oxidized purine. Low-affinity high-capacity sodium:urate cotransporter, may regulate serum urate levels by serving as a renal urate re-absorber. Isoform 2: Inactive transporter. |
Protein Name | Solute Carrier Family 23 Member 1Na(+/L-Ascorbic Acid Transporter 1Sodium-Dependent Vitamin C Transporter 1Hsvct1Yolk Sac Permease-Like Molecule 3 |
Database Links | Reactome: R-HSA-196836 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Solute Carrier Family 23 Member 1 antibodyAnti-Na(+/L-Ascorbic Acid Transporter 1 antibodyAnti-Sodium-Dependent Vitamin C Transporter 1 antibodyAnti-Hsvct1 antibodyAnti-Yolk Sac Permease-Like Molecule 3 antibodyAnti-SLC23A1 antibodyAnti-SVCT1 antibodyAnti-YSPL3 antibody |
Information sourced from Uniprot.org