| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC22A9 (40-145) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC22A9 |
| Gene ID: |
114571 |
| Uniprot ID: |
S22A9_HUMAN |
| Immunogen Region: |
40-145 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 40-145 of human SLC22A9 (NP_543142.2). |
| Immunogen Sequence: |
FTAFIPGHRCWVHILDNDTV SDNDTGALSQDALLRISIPL DSNMRPEKCRRFVHPQWQLL HLNGTFPNTSDADMEPCVDG WVYDRISFSSTIVTEWDLVC DSQSLT |
| Tissue Specificity | Specifically expressed in liver (also at protein level). |
| Function | Sodium-independent organic anion transporter, exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones such as estrone 3-sulfate (E1S) and dehydroepiandrosterone sulfate (DHEAS). Can transport the statin pravastatin and may contribute to its disposition into the hepatocytes when the function of OATPs is compromised. It is specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate (propanoate), butyrate (butanoate) and valerate (pentanoate). May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs, in particular butanoate, at the sinusoidal membrane of hepatocytes. |
| Protein Name | Organic Anion Transporter 7Oat7Organic Anion/Short-Chain Fatty Acid ExchangerSolute Carrier Family 22 Member 9 |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane ProteinEnriched At The Sinusoidal Part Of The Plasma Membrane |
| Alternative Antibody Names | Anti-Organic Anion Transporter 7 antibodyAnti-Oat7 antibodyAnti-Organic Anion/Short-Chain Fatty Acid Exchanger antibodyAnti-Solute Carrier Family 22 Member 9 antibodyAnti-SLC22A9 antibodyAnti-hOAT4 antibodyAnti-OAT7 antibodyAnti-UST3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
