Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SLC14A2 (420-580) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SLC14A2 |
Gene ID: |
8170 |
Uniprot ID: |
UT2_HUMAN |
Immunogen Region: |
420-580 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 420-580 of human SLC14A2 (NP_009094.3). |
Immunogen Sequence: |
FRLPLSKVTYPEANRIYYLT VKSGEEEKAPSGGGGEHPPT AGPKVEEGSEAVLSKHRSVF HIEWSSIRRRSKVFGKGEHQ ERQNKDPFPYRYRKPTVELL DLDTMEESSEIKVETNISKT SWIRSSMAASGKRVSKALSY ITGEMKECGEGLKDKSPVFQ F |
Tissue Specificity | Isoform 1: Epressed in the inner medulla of the kidney (at protein level). Isoform 2: Expressed in the kidney. |
Function | Isoform 1: Mediates the transport of urea driven by a concentration gradient across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism. Isoform 2: Mediates the transport of urea driven by a concentration gradient across the cell membrane of the kidney inner medullary collecting duct which is critical to the urinary concentrating mechanism. |
Protein Name | Urea Transporter 2Solute Carrier Family 14 Member 2Urea Transporter - Kidney |
Database Links | Reactome: R-HSA-425366 |
Cellular Localisation | Isoform 1: Apical Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
Alternative Antibody Names | Anti-Urea Transporter 2 antibodyAnti-Solute Carrier Family 14 Member 2 antibodyAnti-Urea Transporter - Kidney antibodyAnti-SLC14A2 antibodyAnti-HUT2 antibodyAnti-UT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance