| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC14A2 |
| Gene ID: | 8170 |
| Uniprot ID: | UT2_HUMAN |
| Immunogen Region: | 420-580 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 420-580 of human SLC14A2 (NP_009094.3). |
| Immunogen Sequence: | FRLPLSKVTYPEANRIYYLT VKSGEEEKAPSGGGGEHPPT AGPKVEEGSEAVLSKHRSVF HIEWSSIRRRSKVFGKGEHQ ERQNKDPFPYRYRKPTVELL DLDTMEESSEIKVETNISKT SWIRSSMAASGKRVSKALSY ITGEMKECGEGLKDKSPVFQ F |
| Tissue Specificity | Isoform 1: Epressed in the inner medulla of the kidney (at protein level). Isoform 2: Expressed in the kidney. |
| Function | Isoform 1: Mediates the transport of urea driven by a concentration gradient across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism. Isoform 2: Mediates the transport of urea driven by a concentration gradient across the cell membrane of the kidney inner medullary collecting duct which is critical to the urinary concentrating mechanism. |
| Protein Name | Urea Transporter 2Solute Carrier Family 14 Member 2Urea Transporter - Kidney |
| Database Links | Reactome: R-HSA-425366 |
| Cellular Localisation | Isoform 1: Apical Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Urea Transporter 2 antibodyAnti-Solute Carrier Family 14 Member 2 antibodyAnti-Urea Transporter - Kidney antibodyAnti-SLC14A2 antibodyAnti-HUT2 antibodyAnti-UT2 antibody |
Information sourced from Uniprot.org