| Host: |
Mouse |
| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-SHBG is suitable for use in ELISA research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
6001 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Purification: |
Purity accurate to greater than or equal to 95% |
| Concentration: |
5.0 mg/ml (+/-10 %) |
| Storage Instruction: |
24 months from manufacturing at 2°C. Temperature analysis:-70 °C, 21 days N/D-20 °C, 21 days OK +4 °C, 21 days OK +30 °C, 21 days OK +35 °C, 7 days OK +35 °C, 21 days Failed due to reduced antigen binding +45 °C, 3 days OK +45 °C, 7 days OK, some cha |
| Determination Method: |
Radioimmunoassay (RIA) |
| Immunoreactivity: |
80–120 % compared to the reference sample in an FIA test |
| Gene Symbol: |
SHBG |
| Gene ID: |
6462 |
| Uniprot ID: |
SHBG_HUMAN |
| Immunogen: |
human sex hormone-binding globulin |
| Tissue Specificity | Isoform 1 and isoform 2 are present in liver and testis. |
| Post Translational Modifications | Variant Asn-356 contains one N-linked (GlcNAc..) at position 356. |
| Function | Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. |
| Protein Name | Sex Hormone-Binding GlobulinShbgSex Steroid-Binding ProteinSbpTestis-Specific Androgen-Binding ProteinAbpTestosterone-Estradiol-Binding GlobulinTebgTestosterone-Estrogen-Binding Globulin |
| Cellular Localisation | SecretedIn TestisIt Is Synthesized By The Sertoli CellsSecreted Into The Lumen Of The Seminiferous Tubule And Transported To The Epididymis |
| Alternative Antibody Names | Anti-Sex Hormone-Binding Globulin antibodyAnti-Shbg antibodyAnti-Sex Steroid-Binding Protein antibodyAnti-Sbp antibodyAnti-Testis-Specific Androgen-Binding Protein antibodyAnti-Abp antibodyAnti-Testosterone-Estradiol-Binding Globulin antibodyAnti-Tebg antibodyAnti-Testosterone-Estrogen-Binding Globulin antibodyAnti-SHBG antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
