| Host: | Mouse |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-SHBG is suitable for use in ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 6001 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Purification: | Purity accurate to greater than or equal to 95% |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Storage Instruction: | 24 months from manufacturing at 2°C. Temperature analysis:-70 °C, 21 days N/D-20 °C, 21 days OK +4 °C, 21 days OK +30 °C, 21 days OK +35 °C, 7 days OK +35 °C, 21 days Failed due to reduced antigen binding +45 °C, 3 days OK +45 °C, 7 days OK, some cha |
| Determination Method: | Radioimmunoassay (RIA) |
| Immunoreactivity: | 80–120 % compared to the reference sample in an FIA test |
| Gene Symbol: | SHBG |
| Gene ID: | 6462 |
| Uniprot ID: | SHBG_HUMAN |
| Immunogen: | human sex hormone-binding globulin |
| Tissue Specificity | Isoform 1 and isoform 2 are present in liver and testis. |
| Post Translational Modifications | Variant Asn-356 contains one N-linked (GlcNAc..) at position 356. |
| Function | Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. |
| Protein Name | Sex Hormone-Binding Globulin Shbg Sex Steroid-Binding Protein Sbp Testis-Specific Androgen-Binding Protein Abp Testosterone-Estradiol-Binding Globulin Tebg Testosterone-Estrogen-Binding Globulin |
| Cellular Localisation | Secreted In Testis It Is Synthesized By The Sertoli Cells Secreted Into The Lumen Of The Seminiferous Tubule And Transported To The Epididymis |
| Alternative Antibody Names | Anti-Sex Hormone-Binding Globulin antibody Anti-Shbg antibody Anti-Sex Steroid-Binding Protein antibody Anti-Sbp antibody Anti-Testis-Specific Androgen-Binding Protein antibody Anti-Abp antibody Anti-Testosterone-Estradiol-Binding Globulin antibody Anti-Tebg antibody Anti-Testosterone-Estrogen-Binding Globulin antibody Anti-SHBG antibody |
Information sourced from Uniprot.org
