| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SERPINB2 |
| Gene ID: | 5055 |
| Uniprot ID: | PAI2_HUMAN |
| Immunogen Region: | 1-415 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-415 of human SERPINB2 (NP_002566.1). |
| Immunogen Sequence: | MEDLCVANTLFALNLFKHLA KASPTQNLFLSPWSISSTMA MVYMGSRGSTEDQMAKVLQF NEVGANAVTPMTPENFTSCG FMQQIQKGSYPDAILQAQAA DKIHSSFRSLSSAINASTGN YLLESVNKLFGEKSASFREE YIRLCQKYYSSEPQAVDFLE CAEEARKKINSWVKTQTKGK IPNLLPEGSVDGDTRMVLVN AVYFKGKWKTPFEKKLNGLY PFRVNSAQRTPVQMMYLRE |
| Post Translational Modifications | The signal sequence is not cleaved. |
| Function | Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. |
| Protein Name | Plasminogen Activator Inhibitor 2Pai-2Monocyte Arg-SerpinPlacental Plasminogen Activator InhibitorSerpin B2Urokinase Inhibitor |
| Database Links | Reactome: R-HSA-75205Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmSecretedExtracellular Space |
| Alternative Antibody Names | Anti-Plasminogen Activator Inhibitor 2 antibodyAnti-Pai-2 antibodyAnti-Monocyte Arg-Serpin antibodyAnti-Placental Plasminogen Activator Inhibitor antibodyAnti-Serpin B2 antibodyAnti-Urokinase Inhibitor antibodyAnti-SERPINB2 antibodyAnti-PAI2 antibodyAnti-PLANH2 antibody |
Information sourced from Uniprot.org