| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SERPINA12 |
| Gene ID: | 145264 |
| Uniprot ID: | SPA12_HUMAN |
| Immunogen Region: | 20-320 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human SERPINA12 (NP_776249.1). |
| Immunogen Sequence: | LLKPSFSPRNYKALSEVQGW KQRMAAKELARQNMDLGFKL LKKLAFYNPGRNIFLSPLSI STAFSMLCLGAQDSTLDEIK QGFNFRKMPEKDLHEGFHYI IHELTQKTQDLKLSIGNTLF IDQRLQPQRKFLEDAKNFYS AETILTNFQNLEMAQKQIND FISQKTHGKINNLIENIDPG TVMLLANYIFFRARWKHEFD PNVTKEEDFFLEKNSSVKVP MMFRSGIYQVGYDDKLSCT |
| Tissue Specificity | Expressed in visceral adipose tissues. |
| Post Translational Modifications | Glycosylation slightly decreases affinity for heparin, but otherwise has no significant effect on KLK7 inhibitory activity or thermal stability of the protein. |
| Function | Adipokine that modulates insulin action by specifically inhibiting its target protease KLK7 in white adipose tissues. |
| Protein Name | Serpin A12Ol-64Visceral Adipose Tissue-Derived Serine Protease InhibitorVaspinVisceral Adipose-Specific Serpin |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Serpin A12 antibodyAnti-Ol-64 antibodyAnti-Visceral Adipose Tissue-Derived Serine Protease Inhibitor antibodyAnti-Vaspin antibodyAnti-Visceral Adipose-Specific Serpin antibodyAnti-SERPINA12 antibody |
Information sourced from Uniprot.org