| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SEMA4C |
| Gene ID: | 54910 |
| Uniprot ID: | SEM4C_HUMAN |
| Immunogen Region: | 749-833 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 749-833 of human SEMA4C (NP_060259.4). |
| Immunogen Sequence: | HARCQPGGGPPSPPPGIPGQ PLPSPTRLHLGGGRNSNANG YVRLQLGGEDRGGLGHPLPE LADELRRKLQQRQPLPDSNP EESSV |
| Function | Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. |
| Protein Name | Semaphorin-4c |
| Cellular Localisation | Postsynaptic Density MembraneSingle-Pass Type I Membrane ProteinCytoplasmic VesicleSecretory VesicleSynaptic Vesicle Membrane |
| Alternative Antibody Names | Anti-Semaphorin-4c antibodyAnti-SEMA4C antibodyAnti-KIAA1739 antibodyAnti-SEMAI antibodyAnti-UNQ5855 antibodyAnti-PRO34487 antibody |
Information sourced from Uniprot.org