• Western blot analysis of the lysates from COLO205 cells using SCN4A antibody.
  • Western blot analysis of SCN4A Antibody. The lane on the right is blocked with the SCN4A peptide.

Anti-SCN4A antibody (431-480) (STJ94331)

SKU:
STJ94331

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Sodium channel protein type 4 subunit alpha (431-480) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-p 1:50-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SCN4A
Gene ID: 6329
Uniprot ID: SCN4A_HUMAN
Immunogen Region: 431-480
Specificity: Na+ CP type IV Alpha Polyclonal Antibody detects endogenous levels of Na+ CP type IV Alpha protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human SCN4A. AA range:431-480
Post Translational Modifications Phosphorylation at Ser-1328 by PKC in a highly conserved cytoplasmic loop slows inactivation of the sodium channel and reduces peak sodium currents.
Function Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles, and constant muscle strength in the presence of fluctuating K(+) levels.
Protein Name Sodium Channel Protein Type 4 Subunit Alpha
Skm1
Sodium Channel Protein Skeletal Muscle Subunit Alpha
Sodium Channel Protein Type Iv Subunit Alpha
Voltage-Gated Sodium Channel Subunit Alpha Nav1.4
Database Links Reactome: R-HSA-445095
Reactome: R-HSA-5576892
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Sodium Channel Protein Type 4 Subunit Alpha antibody
Anti-Skm1 antibody
Anti-Sodium Channel Protein Skeletal Muscle Subunit Alpha antibody
Anti-Sodium Channel Protein Type Iv Subunit Alpha antibody
Anti-Voltage-Gated Sodium Channel Subunit Alpha Nav1.4 antibody
Anti-SCN4A antibody

Information sourced from Uniprot.org

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