• Immunofluorescence analysis of U-2 OS cells using SCGB3A2 Rabbit polyclonal antibody (STJ115103) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of L929 cells using SCGB3A2 Rabbit polyclonal antibody (STJ115103) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of C6 cells using SCGB3A2 Rabbit polyclonal antibody (STJ115103) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of various lysates using SCGB3A2 Rabbit polyclonal antibody (STJ115103) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-SCGB3A2 antibody (1-93) (STJ115103)

SKU:
STJ115103

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SCGB3A2
Gene ID: 117156
Uniprot ID: SG3A2_HUMAN
Immunogen Region: 1-93
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-93 of human SCGB3A2 (NP_473364.1).
Immunogen Sequence: MKLVTIFLLVTISLCSYSAT AFLINKVPLPVDKLAPLPLD NILPFMDPLKLLLKTLGISV EHLVEGLRKCVNELGPEASE AVKKLLEALSHLV
Tissue Specificity Highly expressed in lung and trachea. Detected throughout the airway epithelium in lung, with slightly higher expression in large airways. Found in lung submucosal gland acinus where it localizes to serous-like cells. Probably expressed in club cells of the bronchioles. Not detected in other tissues tested.
Function Secreted cytokine-like protein. Binds to the scavenger receptor MARCO. Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast. Strongly inhibits phospholipase A2 (PLA2G1B) activity. Seems to have anti-inflammatory effects in respiratory epithelium. Also has anti-fibrotic activity in lung. May play a role in fetal lung development and maturation. Promotes branching morphogenesis during early stages of lung development. In the pituitary, may inhibit production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Protein Name Secretoglobin Family 3a Member 2
Pneumo Secretory Protein 1
Pnsp-1
Uteroglobin-Related Protein 1
Database Links Reactome: R-HSA-3000480
Cellular Localisation Secreted
Alternative Antibody Names Anti-Secretoglobin Family 3a Member 2 antibody
Anti-Pneumo Secretory Protein 1 antibody
Anti-Pnsp-1 antibody
Anti-Uteroglobin-Related Protein 1 antibody
Anti-SCGB3A2 antibody
Anti-PNSP1 antibody
Anti-UGRP1 antibody
Anti-UNQ566 antibody
Anti-PRO1128 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance