| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RSG1 (1-220) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CPLANE2 |
| Gene ID: |
79363 |
| Uniprot ID: |
CPLN2_HUMAN |
| Immunogen Region: |
1-220 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human RSG1 (NP_112169.2). |
| Immunogen Sequence: |
MARPPVPGSVVVPNWHESAE GKEYLACILRKNRRRVFGLL ERPVLLPPVSIDTASYKIFV SGKSGVGKTALVAKLAGLEV PVVHHETTGIQTTVVFWPAK LQASSRVVMFRFEFWDCGES ALKKFDHMLLACMENTDAFL FLFSFTDRASFEDLPGQLAR IAGEAPGVVRMVIGSKFDQY MHTDVPERDLTAFRQAWELP LLRVKSVPGRRLADGRTLDG |
| Function | Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells. |
| Protein Name | Ciliogenesis And Planar Polarity Effector 2Rem2- And Rab-Like Small Gtpase 1 |
| Cellular Localisation | CytoplasmCytoskeletonCilium Basal Body |
| Alternative Antibody Names | Anti-Ciliogenesis And Planar Polarity Effector 2 antibodyAnti-Rem2- And Rab-Like Small Gtpase 1 antibodyAnti-CPLANE2 antibodyAnti-C1orf89 antibodyAnti-RSG1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98774/382822/STJ119989_1__22320.1713151321.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and Emerin/Emerin/EMD knockout (KO) 293T cells, using [KO Validated] Emerin/EMD Rabbit polyclonal antibody (STJ119989) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")