| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ROBO3 (1-147) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ROBO3 |
| Gene ID: |
64221 |
| Uniprot ID: |
ROBO3_HUMAN |
| Immunogen Region: |
1-147 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human ROBO3 (NP_071765.2). |
| Immunogen Sequence: |
MLRYLLKTLLQMNLFADSLA GDISNSSELLLGFNSSLAAL NHTLLPPGDPSLNGSRVGPE DAMPRIVEQPPDLLVSRGEP ATLPCRAEGRPRPNIEWYKN GARVATVREDPRAHRLLLPS GALFFPRIVHGRRARPDEGV YTCVARN |
| Function | Thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube. In spinal cord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1. Required for hindbrain axon midline crossing. |
| Protein Name | Roundabout Homolog 3Roundabout-Like Protein 3 |
| Database Links | Reactome: R-HSA-428542 Q96MS0-1Reactome: R-HSA-9010553 Q96MS0-1Reactome: R-HSA-9010642 Q96MS0-1 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Roundabout Homolog 3 antibodyAnti-Roundabout-Like Protein 3 antibodyAnti-ROBO3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
