Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase RNF170 is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
RNF170 |
Gene ID: |
81790 |
Uniprot ID: |
RN170_HUMAN |
Specificity: |
This antibody detects endogenous levels of RNF170 at Human, Mouse |
Immunogen: |
Synthesized peptide derived from human RNF170 |
Function | E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells. |
Protein Name | E3 Ubiquitin-Protein Ligase Rnf170Putative Lag1-Interacting ProteinRing Finger Protein 170Ring-Type E3 Ubiquitin Transferase Rnf170 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Rnf170 antibodyAnti-Putative Lag1-Interacting Protein antibodyAnti-Ring Finger Protein 170 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Rnf170 antibodyAnti-RNF170 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance