• Western blot analysis of lysates from mouse thymus, using RNASEH2B Rabbit polyclonal antibody (STJ116269) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of various lysates using RNASEH2B Rabbit polyclonal antibody (STJ116269) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-RNASEH2B antibody (1-290) (STJ116269)

SKU:
STJ116269

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RNASEH2B (1-290) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RNASEH2B
Gene ID: 79621
Uniprot ID: RNH2B_HUMAN
Immunogen Region: 1-290
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human RNASEH2B (NP_078846.2).
Immunogen Sequence: MAAGVDCGDGVGARQHVFLV SEYLKDASKKMKNGLMFVKL VNPCSGEGAIYLFNMCLQQL FEVKVFKEKHHSWFINQSVQ SGGLLHFATPVDPLFLLLHY LIKADKEGKFQPLDQVVVDN VFPNCILLLKLPGLEKLLHH VTEEKGNPEIDNKKYYKYSK EKTLKWLEKKVNQTVAALKT NNVNVSSRVQSTAFFSGDQA STDKEEDYIRYAHGLISDYI PKELSDDLSKYLKLPEPSA
Tissue Specificity Widely expressed.
Function Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
Protein Name Ribonuclease H2 Subunit B
Rnase H2 Subunit B
Aicardi-Goutieres Syndrome 2 Protein
Ags2
Deleted In Lymphocytic Leukemia 8
Ribonuclease Hi Subunit B
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Ribonuclease H2 Subunit B antibody
Anti-Rnase H2 Subunit B antibody
Anti-Aicardi-Goutieres Syndrome 2 Protein antibody
Anti-Ags2 antibody
Anti-Deleted In Lymphocytic Leukemia 8 antibody
Anti-Ribonuclease Hi Subunit B antibody
Anti-RNASEH2B antibody
Anti-DLEU8 antibody

Information sourced from Uniprot.org

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