| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Regulator of G-protein signaling 1 (118-167 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RGS1 |
| Gene ID: | 5996 |
| Uniprot ID: | RGS1_HUMAN |
| Immunogen Region: | 118-167 aa |
| Specificity: | RGS1 Polyclonal Antibody detects endogenous levels of RGS1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human RGS1 at the amino acid range 118-167 |
| Function | Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors. Inhibits B cell chemotaxis toward CXCL12. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. |
| Protein Name | Regulator Of G-Protein Signaling 1Rgs1B-Cell Activation Protein Bl34Early Response Protein 1r20 |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytosol |
| Alternative Antibody Names | Anti-Regulator Of G-Protein Signaling 1 antibodyAnti-Rgs1 antibodyAnti-B-Cell Activation Protein Bl34 antibodyAnti-Early Response Protein 1r20 antibodyAnti-RGS1 antibodyAnti-1R20 antibodyAnti-BL34 antibodyAnti-IER1 antibody |
Information sourced from Uniprot.org