| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RGR |
| Gene ID: | 5995 |
| Uniprot ID: | RGR_HUMAN |
| Immunogen Region: | 156-295 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 156-295 of human RGR (NP_002912.2). |
| Immunogen Sequence: | HYDYEPLGTCCTLDYSKGDR NFTSFLFTMSFFNFAMPLFI TITSYSLMEQKLGKSGHLQV NTTLPARTLLLGWGPYAILY LYAVIADVTSISPKLQMVPA LIAKMVPTINAINYALGNEM VCRGIWQCLSPQKREKDRTK |
| Tissue Specificity | Preferentially expressed at high levels in the retinal pigment epithelium (RPE) and Mueller cells of the neural retina. |
| Post Translational Modifications | Covalently binds all-trans- and 11-cis-retinal. |
| Function | Receptor for all-trans- and 11-cis-retinal. Binds preferentially to the former and may catalyze the isomerization of the chromophore by a retinochrome-like mechanism. |
| Protein Name | Rpe-Retinal G Protein-Coupled Receptor |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-419771 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Rpe-Retinal G Protein-Coupled Receptor antibodyAnti-RGR antibody |
Information sourced from Uniprot.org