| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | REV1 |
| Gene ID: | 51455 |
| Uniprot ID: | REV1_HUMAN |
| Immunogen Region: | 120-345 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-345 of human REV1 (NP_057400.1). |
| Immunogen Sequence: | AGRLLSYIPYQLYTKQSSVQ KGLSFNPVCRPEDPLPGPSN IAKQLNNRVNHIVKKIETEN EVKVNGMNSWNEEDENNDFS FVDLEQTSPGRKQNGIPHPR GSTAIFNGHTPSSNGALKTQ DCLVPMVNSVASRLSPAFSQ EEDKAEKSSTDFRDCTLQQL QQSTRNTDALRNPHRTNSFS LSPLHSNTKINGAHHSTVQG PSSTKSTSSVSTFSKAAPSV PSKPSD |
| Tissue Specificity | Ubiquitous. |
| Function | Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. |
| Protein Name | Dna Repair Protein Rev1Alpha Integrin-Binding Protein 80Aibp80Rev1-Like Terminal Deoxycytidyl Transferase |
| Database Links | Reactome: R-HSA-110312Reactome: R-HSA-5655862Reactome: R-HSA-5656121Reactome: R-HSA-5656169 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna Repair Protein Rev1 antibodyAnti-Alpha Integrin-Binding Protein 80 antibodyAnti-Aibp80 antibodyAnti-Rev1-Like Terminal Deoxycytidyl Transferase antibodyAnti-REV1 antibodyAnti-REV1L antibody |
Information sourced from Uniprot.org