• Western blot analysis of extracts of various cell lines, using Renin Rabbit monoclonal antibody (STJ11102290) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.

Anti-REN antibody (1-100) [S0MR] (STJ11102290)

SKU:
STJ11102290

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Renin (1-100) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S0MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: REN
Gene ID: 5972
Uniprot ID: RENI_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Renin (P00797).
Immunogen Sequence: MDGWRRMPRWGLLLLLWGSC TFGLPTDTTTFKRIFLKRMP SIRESLKERGVDMARLGPEW SQPMKRLTLGNTTSSVILTN YMDTQYYGEIGIGTPPQTFK
Function Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
Protein Name Renin
Angiotensinogenase
Database Links Reactome: R-HSA-2022377
Cellular Localisation Secreted
Membrane
Associated To Membranes Via Binding To Atp6ap2
Alternative Antibody Names Anti-Renin antibody
Anti-Angiotensinogenase antibody
Anti-REN antibody

Information sourced from Uniprot.org

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