Anti-Recombinant-SPINK5 antibody [RM2K34] (STJA0025899)

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STJA0025899
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Serine Protease Inhibitor Kazal-Type 5 is suitable for use in Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2K34
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: SPINK5
Gene ID: 11005
Uniprot ID: ISK5_HUMAN
Post Translational Modifications Proteolytically processed by furin in individual domains (D1, D5, D6, D8 through D11, and D9 through D15) exhibiting various inhibitory potentials for multiple proteases.
Function Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation-involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin.
Protein Name Serine Protease Inhibitor Kazal-Type 5
Lympho-Epithelial Kazal-Type-Related Inhibitor
Lekti Cleaved Into - Hemofiltrate Peptide Hf6478 - Hemofiltrate Peptide Hf7665
Database Links Reactome: R-HSA-6809371
Reactome: R-HSA-9725554
Cellular Localisation Secreted
Alternative Antibody Names Anti-Serine Protease Inhibitor Kazal-Type 5 antibody
Anti-Lympho-Epithelial Kazal-Type-Related Inhibitor antibody
Anti-Lekti Cleaved Into - Hemofiltrate Peptide Hf6478 - Hemofiltrate Peptide Hf7665 antibody
Anti-SPINK5 antibody

Information sourced from Uniprot.org

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