Anti-Recombinant-HAMP/Hepcidin antibody [RM2B43] (STJA0025116)

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STJA0025116
£309.50 - £472.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Hepcidin is suitable for use in Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2B43
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: HAMP
Gene ID: 57817
Uniprot ID: HEPC_HUMAN
Function Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes. Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa.
Protein Name Hepcidin
Liver-Expressed Antimicrobial Peptide 1
Leap-1
Putative Liver Tumor Regressor
Pltr Cleaved Into - Hepcidin-25
Hepc25 - Hepcidin-20
Hepc20
Cellular Localisation Secreted
Alternative Antibody Names Anti-Hepcidin antibody
Anti-Liver-Expressed Antimicrobial Peptide 1 antibody
Anti-Leap-1 antibody
Anti-Putative Liver Tumor Regressor antibody
Anti-Pltr Cleaved Into - Hepcidin-25 antibody
Anti-Hepc25 - Hepcidin-20 antibody
Anti-Hepc20 antibody
Anti-HAMP antibody
Anti-HEPC antibody
Anti-LEAP1 antibody
Anti-UNQ487 antibody
Anti-PRO1003 antibody

Information sourced from Uniprot.org